[HTML][HTML] Sfb2p, a yeast protein related to Sec24p, can function as a constituent of COPII coats required for vesicle budding from the endoplasmic reticulum
H Higashio, Y Kimata, T Kiriyama, A Hirata… - Journal of Biological …, 2000 - ASBMB
The COPII coat is required for vesicle budding from the endoplasmic reticulum (ER), and
consists of two heterodimeric subcomplexes, Sec23p/Sec24p, Sec13p/Sec31p, and a small
GTPase, Sar1p. We characterized a yeast mutant, anu1 (abnormalnuclear morphology)
exhibiting proliferated ER as well as abnormal nuclear morphology at the restrictive
temperature. Based on the finding that ANU1 is identical to SEC24, we confirmed a
temperature-sensitive protein transport from the ER to the Golgi in anu1-1/sec24-20 cells …
consists of two heterodimeric subcomplexes, Sec23p/Sec24p, Sec13p/Sec31p, and a small
GTPase, Sar1p. We characterized a yeast mutant, anu1 (abnormalnuclear morphology)
exhibiting proliferated ER as well as abnormal nuclear morphology at the restrictive
temperature. Based on the finding that ANU1 is identical to SEC24, we confirmed a
temperature-sensitive protein transport from the ER to the Golgi in anu1-1/sec24-20 cells …