Genetic dissection of glucocorticoid receptor function in mice
F Tronche, C Kellendonk, HM Reichardt… - Current opinion in …, 1998 - Elsevier
Current opinion in genetics & development, 1998•Elsevier
Upon hormone binding, the activated glucocorticoid receptor (GR) functions as a
transcription factor via different modes of action to control gene expression. Recent gene-
targeting studies in mice provide new insight into the role of GR in vivo and are helping
decipher the molecular mechanisms underlying its actions.
transcription factor via different modes of action to control gene expression. Recent gene-
targeting studies in mice provide new insight into the role of GR in vivo and are helping
decipher the molecular mechanisms underlying its actions.
Upon hormone binding, the activated glucocorticoid receptor (GR) functions as a transcription factor via different modes of action to control gene expression. Recent gene-targeting studies in mice provide new insight into the role of GR in vivo and are helping decipher the molecular mechanisms underlying its actions.
Elsevier