Role of viscogens on the macromolecular assemblies of fibrinogen at liquid/air and solid/air interfaces

K Sankaranarayanan - Biointerphases, 2015 - pubs.aip.org
In this study, an attempt has been made to understand the organization and association of
fibrinogen (Fg) in solvent environment induced by viscogens such as 1-ethyl 3-methyl
imidazolium ethyl sulfate (IL-emes), Ficoll, and Trehalose. The author observed that Fg in IL-
emes adsorbed on solid surface shows higher β-sheet conformation. Shear viscosity
measured using quartz crystal microbalance, for Fg in IL-emes was highest with a
corresponding higher adsorbed mass 3.26 μg/cm 2. Associated assemblies of the protein at …