[HTML][HTML] Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence …
PJ Jakobsson, JA Mancini… - Journal of Biological …, 1996 - ASBMB
5-Lipoxygenase-activating protein (FLAP) and leukotriene C 4 (LTC 4) synthase, two
proteins involved in leukotriene biosynthesis, have been demonstrated to be 31% identical
at the amino acid level. We have recently identified and characterized a novel member of the
FLAP/LTC 4 synthase gene family termed microsomal glutathione S-transferase II
(microsomal GST-II). The open reading frame encodes a 16.6-kDa protein with a calculated
pI of 10.4. Microsomal GST-II has 33% amino acid identity to FLAP, 44% amino acid identity …
proteins involved in leukotriene biosynthesis, have been demonstrated to be 31% identical
at the amino acid level. We have recently identified and characterized a novel member of the
FLAP/LTC 4 synthase gene family termed microsomal glutathione S-transferase II
(microsomal GST-II). The open reading frame encodes a 16.6-kDa protein with a calculated
pI of 10.4. Microsomal GST-II has 33% amino acid identity to FLAP, 44% amino acid identity …