Sphingolipids are a class of bioactive lipids, which are key modulators of an increasing
number of physiologic and pathophysiologic processes that include cell cycle, apoptosis,
angiogenesis, stress and inflammatory responses. Sphingomyelin is an important structural
component of biological membranes, and one of the end-points in the synthesis of
sphingolipids. Mainly synthetized in the Golgi apparatus, sphingomyelin is transported to all
other biological membranes. Upon stimulation, sphingomyelin can be hydrolyzed to …