Effect of interleukin 1β inhibition in cardiovascular disease

A Qamar, DJ Rader - Current opinion in lipidology, 2012 - journals.lww.com
A Qamar, DJ Rader
Current opinion in lipidology, 2012journals.lww.com
IL-1β inhibition offers an interesting and biology-based opportunity to test the potential
beneficial effects of an anti-inflammatory therapeutic strategy in patients with CAD. A large
clinical trial evaluating the impact of IL-1β inhibition in CAD is ongoing and will be an
important test of the inflammation hypothesis in CAD.
Summary
IL-1β inhibition offers an interesting and biology-based opportunity to test the potential beneficial effects of an anti-inflammatory therapeutic strategy in patients with CAD. A large clinical trial evaluating the impact of IL-1β inhibition in CAD is ongoing and will be an important test of the inflammation hypothesis in CAD.
Lippincott Williams & Wilkins