Pretreatment combination reduces remote organ damage secondary to intestinal reperfusion injury in mice: follow-up study

P Stringa, N Lausada, D Romanin, E Portiansky… - Transplantation …, 2016 - Elsevier
Background Intestinal ischemia-reperfusion injury occurs after different surgical treatments,
including intestinal transplantation. This harmful process may have an effect in remote
organs, leading to multiple organ dysfunction syndrome and death. Therefore, to establish
strategies to attenuate local and remote damage constitutes a challenge for experimental
and clinical surgeons in the intestinal surgical field. Methods We evaluated the effect of
ischemic preconditioning and tacrolimus pretreatment applied alone and in combination …