[PDF][PDF] Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1
PD Kwong, JR Mascola, GJ Nabel - Cell host & microbe, 2009 - cell.com
PD Kwong, JR Mascola, GJ Nabel
Cell host & microbe, 2009•cell.comMonoclonal antibodies that effectively neutralize HIV-1 have been widely sought, yet few
have been isolated. Now, technological advances in sera evaluation, B cell stimulation,
microneutralization, and antibody cloning have allowed Burton and colleagues to identify
two broadly neutralizing monoclonal antibodies, PG9 and PG16, which provide insights for
HIV vaccine design.
have been isolated. Now, technological advances in sera evaluation, B cell stimulation,
microneutralization, and antibody cloning have allowed Burton and colleagues to identify
two broadly neutralizing monoclonal antibodies, PG9 and PG16, which provide insights for
HIV vaccine design.
Monoclonal antibodies that effectively neutralize HIV-1 have been widely sought, yet few have been isolated. Now, technological advances in sera evaluation, B cell stimulation, microneutralization, and antibody cloning have allowed Burton and colleagues to identify two broadly neutralizing monoclonal antibodies, PG9 and PG16, which provide insights for HIV vaccine design.
cell.com