Chemokines are key mediators of leukocyte recruitment during immunoregulatory and
proinflammatory responses. CCL20 is a cysteine–cysteine chemokine that was originally
shown to be chemotactic for immature dendritic cells, effector or memory CD4+ T
lymphocytes, and B lymphocytes. Additionally, CCL20 and its only receptor (CCR6) are
exploited by cancer cells for migration and metastatic spread and play important roles in the
development and progression of cancer. However, it still remains unclear how the activity of …