Localization of PKN mRNA in the rat brain

T Hashimoto, H Mukai, T Kawamata, T Taniguchi… - Molecular brain …, 1998 - Elsevier
Distribution of mRNA encoding PKN, a fatty acid and RhoA-activated serine/threonine
protein kinase with a catalytic domain highly homologous to that of protein kinase C, was
investigated in the rat brain using in situ hybridization histochemistry. PKN mRNA proved to
be heterogenously distributed. The highest signals were observed in the cerebellum, in
limbic systems such as olfactory bulb, hippocampal formation and limbic cortex, and in
regions involved in central autonomic and neuroendocrine functions, such as hypothalamic …