A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis
J Esparza-Gordillo, H Schaarschmidt, L Liang… - Journal of allergy and …, 2013 - Elsevier
Background Atopic dermatitis (AD) is a common inflammatory skin disease. Previous studies
have revealed shared genetic determinants among different inflammatory disorders,
suggesting that markers associated with immune-related traits might also play a role in AD.
Objective We sought to identify novel genetic risk factors for AD. Methods We examined the
results of all genome-wide association studies from a public repository and selected 318
genetic markers that were significantly associated with any inflammatory trait. These markers …
have revealed shared genetic determinants among different inflammatory disorders,
suggesting that markers associated with immune-related traits might also play a role in AD.
Objective We sought to identify novel genetic risk factors for AD. Methods We examined the
results of all genome-wide association studies from a public repository and selected 318
genetic markers that were significantly associated with any inflammatory trait. These markers …