Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase
WC Breckenridge, JA Little, P Alaupovic, CS Wang… - Atherosclerosis, 1982 - Elsevier
A hyperlipoproteinemic patient was investigated for lipoprotein abnormalities as a result of
an abnormally high proportion (30%) of triglyceride in low density lipoprotein (LDL), the
presence of β-VLDL as well as a reduced post-heparin lipolytic activity. Analysis of the
component lipase activities in the proband and his brother by selective inactivation with
protamine or by affinity chromatography revealed that lipoprotein lipase was present in
normal concentrations while the triglyceride lipase characteristic of that released from liver …
an abnormally high proportion (30%) of triglyceride in low density lipoprotein (LDL), the
presence of β-VLDL as well as a reduced post-heparin lipolytic activity. Analysis of the
component lipase activities in the proband and his brother by selective inactivation with
protamine or by affinity chromatography revealed that lipoprotein lipase was present in
normal concentrations while the triglyceride lipase characteristic of that released from liver …