Cytotoxic T-lymphocyte antigen 4 gene polymorphism influences the incidence of symptomatic human cytomegalovirus infection after renal transplantation

MK Misra, SK Pandey, R Kapoor… - Pharmacogenetics …, 2015 - journals.lww.com
Background The role of CTLA4 gene polymorphisms in T-cell-mediated immunity in
association with human cytomegalovirus (HCMV) infection after transplantation is poorly
understood. In the present study, we have made an attempt to investigate the impact of
CTLA4 single nucleotide polymorphisms (SNPs)(rs231775, rs5742909, rs11571317,
rs16840252, rs4553808, rs3087243) and dinucleotide (AT) n repeat polymorphism on the
incidence of symptomatic HCMV infection (disease) among 270 renal allograft recipients …