When a food is eaten to satiety, its reward value decreases. This decrease is usually greater
for the food eaten to satiety than for other foods, an effect termed sensory-specific satiety. In
an fMRI investigation it was shown that for a region of the orbitofrontal cortex the activation
produced by the odour of the food eaten to satiety decreased, whereas there was no similar
decrease for the odour of a food not eaten in the meal. This effect was shown both by a voxel-
wise SPM contrast (p< 0.05 corrected) and an ANOVA performed on the mean percentage …