Central nervous system control of metabolism

MG Myers Jr, DP Olson - Nature, 2012 - nature.com
MG Myers Jr, DP Olson
Nature, 2012nature.com
Although it is a widely held thought that direct hormone action on peripheral tissues is
sufficient to mediate the control of nutrient handling, the role of the central nervous system in
certain aspects of metabolism has long been recognized. Furthermore, recent findings have
suggested a more general role for the central nervous system in metabolic control, and have
revealed the importance of a number of cues and hypothalamic circuits. The brain's
contributions to metabolic control are more readily revealed and play a crucial part in …
Abstract
Although it is a widely held thought that direct hormone action on peripheral tissues is sufficient to mediate the control of nutrient handling, the role of the central nervous system in certain aspects of metabolism has long been recognized. Furthermore, recent findings have suggested a more general role for the central nervous system in metabolic control, and have revealed the importance of a number of cues and hypothalamic circuits. The brain's contributions to metabolic control are more readily revealed and play a crucial part in catabolic states or in hormone deficiencies that mimic starvation.
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