Does fructose consumption contribute to non-alcoholic fatty liver disease?
L Tappy, KA Lê - Clinics and research in hepatology and …, 2012 - Elsevier
Fructose is mainly consumed with added sugars (sucrose and high fructose corn syrup), and
represents up to 10% of total energy intake in the US and in several European countries.
This hexose is essentially metabolized in splanchnic tissues, where it is converted into
glucose, glycogen, lactate, and, to a minor extent, fatty acids. In animal models, high fructose
diets cause the development of obesity, insulin resistance, diabetes mellitus, and
dyslipidemia. Ectopic lipid deposition in the liver is an early occurrence upon fructose …
represents up to 10% of total energy intake in the US and in several European countries.
This hexose is essentially metabolized in splanchnic tissues, where it is converted into
glucose, glycogen, lactate, and, to a minor extent, fatty acids. In animal models, high fructose
diets cause the development of obesity, insulin resistance, diabetes mellitus, and
dyslipidemia. Ectopic lipid deposition in the liver is an early occurrence upon fructose …