[HTML][HTML] Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor

J Lin, P Puigserver, J Donovan, P Tarr… - Journal of Biological …, 2002 - ASBMB
Peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) plays a critical role in
regulating multiple aspects of energy metabolism, including adaptive thermogenesis,
mitochondrial biogenesis, and fatty acid β-oxidation. Recently, this coactivator of nuclear
receptors/transcription factors has been shown to control hepatic gluconeogenesis, an
important component of the pathogenesis of both type-1 and type-2 diabetes. We described
here the cloning of a novel bona fide homologue of PGC-1, PGC-1β (PGC-1 was renamed …