[HTML][HTML] Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement
MH Hu, EM Bauman, RL Roll, N Yeilding… - Journal of Biological …, 1999 - ASBMB
We have identified a cDNA for pleckstrin 2 that is 39% identical and 65% homologous to the
original pleckstrin. Like the original pleckstrin 1, this protein contains a pleckstrin homology
(PH) domain at each end of the molecule as well as a DEP (Dishevelled, Egl-10, and
pleckstrin) domain in the intervening sequence. A Northern blot probed with the full-length
cDNA reveals that this homolog is ubiquitously expressed and is most abundant in the
thymus, large bowel, small bowel, stomach, and prostate. Unlike pleckstrin 1, this newly …
original pleckstrin. Like the original pleckstrin 1, this protein contains a pleckstrin homology
(PH) domain at each end of the molecule as well as a DEP (Dishevelled, Egl-10, and
pleckstrin) domain in the intervening sequence. A Northern blot probed with the full-length
cDNA reveals that this homolog is ubiquitously expressed and is most abundant in the
thymus, large bowel, small bowel, stomach, and prostate. Unlike pleckstrin 1, this newly …