Histopathological differential diagnosis of keloid and hypertrophic scar
JYY Lee, CC Yang, SC Chao… - The American journal of …, 2004 - journals.lww.com
Distinguishing hypertrophic scar (HS) from keloid histopathologically is sometimes difficult
because thickened hyalinized collagen (keloidal collagen), the hallmark of keloid, is not
always detectable and α-smooth muscle actin (α-SMA), a differentiating marker of HS, is
variably expressed in both forms of scar. The aim of this study was to investigate additional
distinguishing features to facilitate differentiation between keloid and HS. We compared
various histologic features and the expression of α-SMA in 40 specimens of keloid and 10 …
because thickened hyalinized collagen (keloidal collagen), the hallmark of keloid, is not
always detectable and α-smooth muscle actin (α-SMA), a differentiating marker of HS, is
variably expressed in both forms of scar. The aim of this study was to investigate additional
distinguishing features to facilitate differentiation between keloid and HS. We compared
various histologic features and the expression of α-SMA in 40 specimens of keloid and 10 …
