[HTML][HTML] Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular …
XM Li, Z Hu, ML Jorgenson, JR Wingard… - Experimental …, 2008 - Elsevier
OBJECTIVE: Bone marrow sinusoids remain predominantly host-derived following bone
marrow transplantation. Systematic analysis was conducted at the cellular level to
investigate how the host sinusoidal structures survived after lethal irradiation. MATERIALS
AND METHODS: Apoptosis and cell proliferation assays were performed on bone marrow
sections at various time points during the first 2 weeks postirradiation to study the extent of
damage to sinusoidal endothelial cells from lethal irradiation and to determine whether cell …
marrow transplantation. Systematic analysis was conducted at the cellular level to
investigate how the host sinusoidal structures survived after lethal irradiation. MATERIALS
AND METHODS: Apoptosis and cell proliferation assays were performed on bone marrow
sections at various time points during the first 2 weeks postirradiation to study the extent of
damage to sinusoidal endothelial cells from lethal irradiation and to determine whether cell …