[HTML][HTML] Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor α coregulator
ES Tien, JW Davis, JPV Heuvel - Journal of Biological Chemistry, 2004 - ASBMB
Like other nuclear receptors, the peroxisome proliferator-activated receptors (PPARs) use a
wide variety of protein-protein interactions to properly regulate transcription of target genes.
In an attempt to identify novel PPAR-interacting proteins, a cDNA expression library was
screened with bacterially expressed PPARα. One of the genes identified as a PPARα-
associated protein by interaction cloning was the CREB-binding protein/p300-interacting
transactivator with ED-rich tail 2 (CITED2, also called p35srj/mrg1/msg1). This coactivator …
wide variety of protein-protein interactions to properly regulate transcription of target genes.
In an attempt to identify novel PPAR-interacting proteins, a cDNA expression library was
screened with bacterially expressed PPARα. One of the genes identified as a PPARα-
associated protein by interaction cloning was the CREB-binding protein/p300-interacting
transactivator with ED-rich tail 2 (CITED2, also called p35srj/mrg1/msg1). This coactivator …