[HTML][HTML] Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque
AS Maione, E Cipolletta, D Sorriento, F Borriello… - Atherosclerosis, 2017 - Elsevier
Background and aims Atherosclerosis is a degenerative process of the arterial wall
implicating activation of macrophages and proliferation of vascular smooth muscle cells.
Calcium-calmodulin dependent kinase type II (CaMKII) in vascular smooth muscle cells
(VSMCs) regulates proliferation, while in macrophages, this kinase governs diapedesis,
infiltration and release of extracellular matrix enzymes. We aimed at understanding the
possible role of CaMKII in atherosclerosis plaques to regulate plaque evolution towards …
implicating activation of macrophages and proliferation of vascular smooth muscle cells.
Calcium-calmodulin dependent kinase type II (CaMKII) in vascular smooth muscle cells
(VSMCs) regulates proliferation, while in macrophages, this kinase governs diapedesis,
infiltration and release of extracellular matrix enzymes. We aimed at understanding the
possible role of CaMKII in atherosclerosis plaques to regulate plaque evolution towards …