Fragile fugue: p53 in aging, cancer and IGF signaling

J Campisi - Nature Medicine, 2004 - nature.com
J Campisi
Nature Medicine, 2004nature.com
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Aging is driven in part by an evolutionarily conserved hormone signaling pathway. A new study shows that this pathway is controlled by the p53 tumor suppressor, which exquisitely balances the need for cell proliferation against that for tumor suppression.
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