Systematic analysis of choline-containing phospholipids using multi-dimensional mass spectrometry-based shotgun lipidomics

K Yang, Z Zhao, RW Gross, X Han - Journal of Chromatography B, 2009 - Elsevier
Herein, a systematic study on the identification and quantitation of choline-containing
phospholipid molecular species, including choline glycerophospholipid (PC), lysoPC, and
sphingomyelin (SM), is described using multi-dimensional mass spectrometry-based
shotgun lipidomics after intrasource separation (MDMS-SL). Current methods for analysis of
choline-containing lipids were improved through multiple modifications leading to:(1)
identification of constituents present in the PC and SM classes, subclasses of PC, and …