Publisher Summary This chapter reviews the distribution and specialized differentiation of
macrophages in the nervous system, in the normal state and following injury. Macrophages
are hematopoietic cells that form a long-lived resident population of cells within tissues.
Macrophages are generated in the bone marrow, enter the circulation as monocytes, and
then migrate into almost all tissues of the body. Mature macrophages are highly responsive
to their microenvironment, differing in their morphology and expression of cell surface …