Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

VH Perry, DA Hume, S Gordon - Neuroscience, 1985 - Elsevier
VH Perry, DA Hume, S Gordon
Neuroscience, 1985Elsevier
Macrophages and microglia in the developing and adult mouse brain have been identified
by is consistent with the idea that dying neurons and axons provide a stimulus for
macrophage infiltration. Our results provide strong support for the hypothesis that the
microglia are derived from monocytes and show that microglia possess receptors which
would allow them to play a part in the immune defence of the nervous system.
Abstract
Macrophages and microglia in the developing and adult mouse brain have been identified by is consistent with the idea that dying neurons and axons provide a stimulus for macrophage infiltration.
Our results provide strong support for the hypothesis that the microglia are derived from monocytes and show that microglia possess receptors which would allow them to play a part in the immune defence of the nervous system.
Elsevier