Shiverer: an autosomal recessive mutant mouse with myelin deficiency
GF Chernoff - Journal of Heredity, 1981 - academic.oup.com
GF Chernoff
Journal of Heredity, 1981•academic.oup.comShiverer is an autosomal recessive trait in the mouse characterized by early generalized
tremors that become prominent in the hindquarters with age. Seizure behavior begins after
weaning and increases in frequency during the animal's shortened lifespan. The most
prominent pathological feature is a deficiency of myelin and myelin basic protein in the
central nervous system.
tremors that become prominent in the hindquarters with age. Seizure behavior begins after
weaning and increases in frequency during the animal's shortened lifespan. The most
prominent pathological feature is a deficiency of myelin and myelin basic protein in the
central nervous system.
Abstract
Shiverer is an autosomal recessive trait in the mouse characterized by early generalized tremors that become prominent in the hindquarters with age. Seizure behavior begins after weaning and increases in frequency during the animal's shortened lifespan. The most prominent pathological feature is a deficiency of myelin and myelin basic protein in the central nervous system.
Oxford University Press