Emerging quantitative magnetic resonance imaging biomarkers of hepatic steatosis
SB Reeder - Hepatology, 2013 - journals.lww.com
In this issue of HEPATOLOGY, Noureddin et al. describe an innovative application of an
emerging magnetic resonance imaging (MRI)-based biomarker, proton density fat-fraction
(PDFF), for quantification of hepatic steatosis in patients with nonalcoholic steatohepatitis
(NASH). 1 In this study, 50 patients with biopsy-proven NASH were enrolled in a randomized
double-blinded placebo-controlled trial. Patients were randomized to receive placebo or
colesevelam, an agent known to reduce elevated lowdensity lipoprotein (LDL) and to …
emerging magnetic resonance imaging (MRI)-based biomarker, proton density fat-fraction
(PDFF), for quantification of hepatic steatosis in patients with nonalcoholic steatohepatitis
(NASH). 1 In this study, 50 patients with biopsy-proven NASH were enrolled in a randomized
double-blinded placebo-controlled trial. Patients were randomized to receive placebo or
colesevelam, an agent known to reduce elevated lowdensity lipoprotein (LDL) and to …