PURPOSE: Familial forms of cryptogenic cirrhosis have been described. We have cared for
families in which several members were afflicted with cryptogenic cirrhosis as well as the
more recently recognized entity of nonalcoholic steatohepatitis. To examine the familial
patterns of these disorders, we reviewed patients with nonalcoholic steatohepatitis, with and
without cirrhosis, or cryptogenic cirrhosis to assess how frequently their relatives were
afflicted with these disorders. SUBJECTS AND METHODS: Eighteen members of eight …