High-sensitivity C-reactive protein and risk of nontraumatic fractures in the Bruneck study
G Schett, S Kiechl, S Weger, A Pederiva… - Archives of internal …, 2006 - jamanetwork.com
Background Chronic inflammatory diseases are associated with bone loss and an enhanced
fracture risk. It is unknown, however, whether low-grade inflammation in healthy individuals,
as estimated by the high-sensitivity C-reactive protein (hs-CRP) level, interferes with bone
metabolism and affects the risk of nontraumatic fractures. Methods Lifetime bone fractures
were carefully recorded in the cohort of the population-based Bruneck Study (n= 919) along
with information on the date of occurrence and associated circumstances. The serum level of …
fracture risk. It is unknown, however, whether low-grade inflammation in healthy individuals,
as estimated by the high-sensitivity C-reactive protein (hs-CRP) level, interferes with bone
metabolism and affects the risk of nontraumatic fractures. Methods Lifetime bone fractures
were carefully recorded in the cohort of the population-based Bruneck Study (n= 919) along
with information on the date of occurrence and associated circumstances. The serum level of …