Prothrombin time as an index of mortality in kwashiorkor
OO Akinyinka, AG Falade… - Annals of tropical …, 1990 - Taylor & Francis
OO Akinyinka, AG Falade, CO Ogbechie
Annals of tropical paediatrics, 1990•Taylor & FrancisProthrombin time, serum albumin, aminotransferases and liver size were evaluated in 40
consecutive cases of kwashiorkor. Eleven (27.5%) of the 40 patients died. Eight out of the 11
patients who died had a prolonged prothrombin time of more than 3 s above the control
compared to only 4 out of the 29 who survived (p= 0.005). Mean serum aspartate
aminotransferase (AST), alanine aminotransferase (ALT) albumin, globulin and liver size
were abnormal but similar in both groups. These results may indicate a predictive mortality …
consecutive cases of kwashiorkor. Eleven (27.5%) of the 40 patients died. Eight out of the 11
patients who died had a prolonged prothrombin time of more than 3 s above the control
compared to only 4 out of the 29 who survived (p= 0.005). Mean serum aspartate
aminotransferase (AST), alanine aminotransferase (ALT) albumin, globulin and liver size
were abnormal but similar in both groups. These results may indicate a predictive mortality …
Summary
Prothrombin time, serum albumin, aminotransferases and liver size were evaluated in 40 consecutive cases of kwashiorkor. Eleven (27.5%) of the 40 patients died. Eight out of the 11 patients who died had a prolonged prothrombin time of more than 3 s above the control compared to only 4 out of the 29 who survived (p= 0.005). Mean serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) albumin, globulin and liver size were abnormal but similar in both groups. These results may indicate a predictive mortality value of prothrombin time in kwashiorkor.
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