[HTML][HTML] Interorgan coordination of the murine adaptive response to fasting
TBM Hakvoort, PD Moerland, R Frijters… - Journal of Biological …, 2011 - ASBMB
Starvation elicits a complex adaptive response in an organism. No information on
transcriptional regulation of metabolic adaptations is available. We, therefore, studied the
gene expression profiles of brain, small intestine, kidney, liver, and skeletal muscle in mice
that were subjected to 0–72 h of fasting. Functional-category enrichment, text mining, and
network analyses were employed to scrutinize the overall adaptation, aiming to identify
responsive pathways, processes, and networks, and their regulation. The observed …
transcriptional regulation of metabolic adaptations is available. We, therefore, studied the
gene expression profiles of brain, small intestine, kidney, liver, and skeletal muscle in mice
that were subjected to 0–72 h of fasting. Functional-category enrichment, text mining, and
network analyses were employed to scrutinize the overall adaptation, aiming to identify
responsive pathways, processes, and networks, and their regulation. The observed …