Bile acids and coagulation factors: paradoxical association in children with chronic liver disease

M Magnusson, B Fischler, J Svensson… - European Journal of …, 2013 - journals.lww.com
Objective To examine whether there is an association between bile acids and coagulation
factors in children with chronic liver disease. Methods Forty-five patients (age 2.8 months–
18.8 years) were included in this cross-sectional observational study carried out at a single
tertiary referral center. Coagulation factors, prothrombin time, albumin, and total fasting
serum bile acids were analyzed. The international normalized ratio (INR) and the pediatric
end-stage liver disease score were calculated. Results The 12 patients with bile acids more …