Negative regulatory activity of a prostaglandin F2α receptor associated protein (FPRP)
DJ Orlicky - Prostaglandins, Leukotrienes and Essential Fatty Acids, 1996 - Elsevier
The cDNA has been cloned for a protein which copurifies with and colocalizes with [3H]
PGF2α binding activity. This cloning was based on prior purification of the [3H] PGF2α
binding complex from pregnant corpus luteum, antibody production against the protein of
interest, and antibody screening of a rat ovary cDNA expression library. 1 Here I report on
the activity of this prostaglandin F2α receptor (FP) associated protein (FPRP). Expression of
the FPRP cDNA in COS cells results in production of a full length (≈ 130 kD) …
PGF2α binding activity. This cloning was based on prior purification of the [3H] PGF2α
binding complex from pregnant corpus luteum, antibody production against the protein of
interest, and antibody screening of a rat ovary cDNA expression library. 1 Here I report on
the activity of this prostaglandin F2α receptor (FP) associated protein (FPRP). Expression of
the FPRP cDNA in COS cells results in production of a full length (≈ 130 kD) …