A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
AR Moser, HC Pitot, WF Dove - Science, 1990 - science.org
AR Moser, HC Pitot, WF Dove
Science, 1990•science.orgIn a pedigree derived from a mouse treated with the mutagen ethylnitrosourea, a mutation
has been identified that predisposes to spontaneous intestinal cancer. The mutant gene was
found to be dominantly expressed and fully penetrant. Affected mice developed multiple
adenomas throughout the entire intestinal tract at an early age.
has been identified that predisposes to spontaneous intestinal cancer. The mutant gene was
found to be dominantly expressed and fully penetrant. Affected mice developed multiple
adenomas throughout the entire intestinal tract at an early age.
In a pedigree derived from a mouse treated with the mutagen ethylnitrosourea, a mutation has been identified that predisposes to spontaneous intestinal cancer. The mutant gene was found to be dominantly expressed and fully penetrant. Affected mice developed multiple adenomas throughout the entire intestinal tract at an early age.
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