BACKGROUND: Pre-gravid obesity is associated with increased morbidity and mortality for
both mother and offspring. Recent studies have demonstrated a heightened inflammatory
response both systemically and locally within the adipose and placental tissue in women
with pre-gravid obesity, which may play a role in mediating the adverse pregnancy
outcomes. The aim of this study was to characterise the maternal and placental inflammatory
status and investigate associated changes in placental structure in obese women …