Obesity and inflammation: evidence for an elementary lesion

A Sbarbati, F Osculati, D Silvagni, D Benati… - …, 2006 - publications.aap.org
In obesity, an inflammatory process of the adipose tissue has been hypothesized; however,
direct evidence for a tissue lesion is still lacking. Macrophage infiltration in the adipose
tissue of obese individuals seems to be proven, but other alterations of the tissue have not
been demonstrated. Moreover, in humans it has not been clarified whether inflammation is
an early characteristic of obesity, because no data from obese children are available. In the
present study, we assessed the inflammatory involvement of the adipose tissue and …