Presently, the major histocompatibility complex (MHC) is receiving considerable interest
owing to its remarkable role in antigen presentation and vaccine design. The specific
databases and prediction approaches related to MHC sequences, structures and
binding/nonbinding peptides have been aggressively developed in the past two decades
with their own benchmarks and standards. Before using these databases and prediction
tools, it is important to analyze why and how the tools are constructed along with their …