Oxidative stress and hypertension
DG Harrison, MC Gongora - Medical Clinics, 2009 - medical.theclinics.com
Reactive oxygen species (ROS) are metabolites of oxygen that can either strip electrons
away from other molecules (oxidize), donate electrons to molecules (reduce), or react with
and become part of molecules (ie, oxidative modification). Many ROS possess an unpaired
electron in their outer orbital and are, therefore, radicals. A particularly important radical for
cardiovascular biology is superoxide (O2$–), which is formed by the one-electron reduction
of oxygen (Fig. 1). O2$–is important because it can serve as both an oxidant and as a …
away from other molecules (oxidize), donate electrons to molecules (reduce), or react with
and become part of molecules (ie, oxidative modification). Many ROS possess an unpaired
electron in their outer orbital and are, therefore, radicals. A particularly important radical for
cardiovascular biology is superoxide (O2$–), which is formed by the one-electron reduction
of oxygen (Fig. 1). O2$–is important because it can serve as both an oxidant and as a …