White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response
to altered energy balance. Research conducted for over 70 years has investigated adipose
tissue plasticity on a cellular level, spurred on by the increasing burden that obesity and
associated diseases are placing on public health globally. This work has identified
committed preadipocytes in the stromal vascular fraction of adipose tissue and led to our …