Treatment-time-dependence models of early and delayed radiation injury in rat small intestine
JW Denham, M Hauer-Jensen, T Kron… - International Journal of …, 2000 - Elsevier
Background: The present study modeled data from a large series of experiments originally
designed to investigate the influence of time, dose, and fractionation on early and late
pathologic endpoints in rat small intestine after localized irradiation. The objective was to
obtain satisfactory descriptions of the regenerative response to injury together with the
possible relationships between early and late endpoints. Methods: Two-and 26-week
pathologic radiation injury data in groups of Sprague–Dawley rats irradiated with 27 different …
designed to investigate the influence of time, dose, and fractionation on early and late
pathologic endpoints in rat small intestine after localized irradiation. The objective was to
obtain satisfactory descriptions of the regenerative response to injury together with the
possible relationships between early and late endpoints. Methods: Two-and 26-week
pathologic radiation injury data in groups of Sprague–Dawley rats irradiated with 27 different …