Linking gene regulation to mRNA production and export

S Rodríguez-Navarro, E Hurt - Current opinion in cell biology, 2011 - Elsevier
Current opinion in cell biology, 2011Elsevier
Regulation of gene expression can occur at many different levels. One important step in the
gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In
recent years, studies have described how nuclear mRNA export depends on the steps
preceding and following transport through nuclear pore complexes. These include gene
activation, transcription, mRNA processing and mRNP assembly and disassembly. In this
review, we summarise recent insights into the links between these steps in the gene …
Regulation of gene expression can occur at many different levels. One important step in the gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In recent years, studies have described how nuclear mRNA export depends on the steps preceding and following transport through nuclear pore complexes. These include gene activation, transcription, mRNA processing and mRNP assembly and disassembly. In this review, we summarise recent insights into the links between these steps in the gene expression cascade.
Elsevier