A comparison of a manual and an automated behavioural analysis method for assessing post-operative pain in mice

AL Miller, PA Flecknell, MC Leach… - Applied Animal Behaviour …, 2011 - Elsevier
Current methods of identifying and analysing behavioural signs of pain in mice are highly
time consuming and labour intensive. HomeCageScan (HCS) is an automated analysis
system that may offer an alternative to manual scoring. Thirty-two male mice undergoing
vasectomy were filmed before and at 1h following surgery. Their behaviour was analysed by
manual scoring and using an automated system (HCS; Clever Systems Inc.). The methods
were compared using Bland–Altman plots, indicating a good level of agreement between …