Progress in the genetics of common obesity: size matters
S Li, RJF Loos - Current opinion in lipidology, 2008 - journals.lww.com
S Li, RJF Loos
Current opinion in lipidology, 2008•journals.lww.comGenome-wide association promises to enhance greatly our understanding of the genetic
basis of common obesity, although candidate gene studies will remain a valuable approach
because they allow more detailed analyses of biologically relevant candidates. A key factor
contributing to continued success lies in large-scale data integration through international
collaboration, which will provide the sample sizes required to identify genetic association
with conclusive evidence.
basis of common obesity, although candidate gene studies will remain a valuable approach
because they allow more detailed analyses of biologically relevant candidates. A key factor
contributing to continued success lies in large-scale data integration through international
collaboration, which will provide the sample sizes required to identify genetic association
with conclusive evidence.
Summary
Genome-wide association promises to enhance greatly our understanding of the genetic basis of common obesity, although candidate gene studies will remain a valuable approach because they allow more detailed analyses of biologically relevant candidates. A key factor contributing to continued success lies in large-scale data integration through international collaboration, which will provide the sample sizes required to identify genetic association with conclusive evidence.
Lippincott Williams & Wilkins