Objective To determine the sensitivity of T2*-weighted gradient-echo (T2* GRE) and
inversion recovery turbo-field-echo (TFE) sequences for cortical multiple sclerosis lesions at
7 T. Design, Setting, and Participants Autopsied brain tissue from individuals with multiple
sclerosis was scanned with 3-dimensional T2* GRE and 3-dimensional inversion recovery
white matter–attenuated TFE sequences at 7 T. Cortical lesions visible with either sequence
were scored for each anatomical lesion type. Imaged brain tissue was then processed for …