T cells and B cells in lupus nephritis

MH Foster - Seminars in nephrology, 2007 - Elsevier
T and B lymphocytes play diverse roles at multiple stages in the development and
progression of lupus nephritis. Disruption of T-and B-cell regulatory functions by
environmental and genetic influences permits pathogenic effectors to emerge in disease.
New insights into the biology of these multifunctional cells offer novel targets for intervention
in lupus nephritis and systemic autoimmunity.