Potential mechanisms for the emerging link between obesity and increased intestinal permeability

TFS Teixeira, MC Collado, CLLF Ferreira, J Bressan… - Nutrition research, 2012 - Elsevier
Recently, increased attention has been paid to the link between gut microbial composition
and obesity. Gut microbiota is a source of endotoxins whose increase in plasma is related to
obesity and insulin resistance through increased intestinal permeability in animal models;
however, this relationship still needs to be confirmed in humans. That intestinal permeability
is subject to change and that it might be the interface between gut microbiota and
endotoxins in the core of metabolic dysfunctions reinforce the need to understand the …