[PDF][PDF] Degradation of neutrophil extracellular traps is decreased in patients with antiphospholipid syndrome
J Leffler, L Stojanovich, Y Shoenfeld… - Clin Exp …, 2014 - academia.edu
Clin Exp Rheumatol, 2014•academia.edu
Objective A decreased ability to degrade neutrophil extracellular traps (NETs) is seen in a
subgroup of patients with systemic lupus erythematosus (SLE) and correlates with the
presence of autoantibodies. Antiphospholipid syndrome (APS) can develop secondary to
SLE or as a primary disease. In the current study we investigated the ability of sera from
patients with APS to degrade NETs. The presence of antibodies against NETs and
neutrophil remnants were also determined in the same patients.
subgroup of patients with systemic lupus erythematosus (SLE) and correlates with the
presence of autoantibodies. Antiphospholipid syndrome (APS) can develop secondary to
SLE or as a primary disease. In the current study we investigated the ability of sera from
patients with APS to degrade NETs. The presence of antibodies against NETs and
neutrophil remnants were also determined in the same patients.
Objective
A decreased ability to degrade neutrophil extracellular traps (NETs) is seen in a subgroup of patients with systemic lupus erythematosus (SLE) and correlates with the presence of autoantibodies. Antiphospholipid syndrome (APS) can develop secondary to SLE or as a primary disease. In the current study we investigated the ability of sera from patients with APS to degrade NETs. The presence of antibodies against NETs and neutrophil remnants were also determined in the same patients.
academia.edu