[HTML][HTML] CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family
CG Lin, SJ Leu, N Chen, CM Tebeau, SX Lin… - Journal of Biological …, 2003 - ASBMB
CCN3 (NOV) is a matricellular protein of the CCN family, which also includes CCN1
(CYR61), CCN2 (CTGF), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3). During
development, CCN3 is expressed widely in derivatives of all three germ layers, and high
levels of expression are observed in smooth muscle cells of the arterial vessel wall. Altered
expression of CCN3 has been observed in a variety of tumors, including hepatocellular
carcinomas, Wilm's tumors, Ewing's sarcomas, gliomas, rhabdomyosarcomas, and …
(CYR61), CCN2 (CTGF), CCN4 (WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3). During
development, CCN3 is expressed widely in derivatives of all three germ layers, and high
levels of expression are observed in smooth muscle cells of the arterial vessel wall. Altered
expression of CCN3 has been observed in a variety of tumors, including hepatocellular
carcinomas, Wilm's tumors, Ewing's sarcomas, gliomas, rhabdomyosarcomas, and …