Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance

O Fadare, SX Liang, MA Crispens, HW Jones III… - Human pathology, 2013 - Elsevier
Insulin-like growth factor-II messenger RNA–binding protein 3 (IGF2BP3 or IMP3) is a
biomarker whose expression has been found to be a negative prognostic factor in several
neoplasms including ovarian clear cell carcinoma (CCC). In this study, we analyzed the
frequency and clinicopathologic significance of IMP3 expression, as assessed by
immunohistochemistry and as scored using a modified H-score system, in a cohort of 50
endometrial CCCs. Cases with scores of 0 to 100, 101 to 200, and 201 to 300 were …